Case Presentation in Advanced Colon Cancer Case: 2
Case Presentation in Advanced Colon Cancer
- A 55-year old Caucasian male was admitted to the hospital with severe crampy right lower quadrant pain
- He had a 2-month history of constipation, general abdominal discomfort, and tiredness
- PMH remarkable for hyperlipidemia managed with diet and statin therapy
- Laboratory findings remarkable for grade 2 anemia (Hb, 9.0 g/dL) and elevated CEA (6.7 ng/mL)
- CT showed a non-obstructive mass in the sigmoid colon that infiltrated the full thickness of the bowel wall and involved adipose tissue
- Biopsy results indicated poorly differentiated invasive adenocarcinoma
- He opted for sigmoid colectomy and was referred to a surgeon
- Following surgery, R0 resection with clear margins
- 9 of 13 lymph nodes sampled were positive for adenocarcinoma
Retrospective Data Demonstrates Efficacy of Regorafenib in mCRC
April 16th 2024During a Case-Based Roundtable® event, Madappa Kundranda, MD, PhD, discussed recent retrospective studies that compared outcomes between the available treatment options in patients with relapsed/refractory advanced colorectal cancer in the first article of a 2-part series.
Read More
Peritoneal RFS May Be a Stronger Predictor of OS in CRC Peritoneal Metastasis
March 27th 2024In an interview with Targeted Oncology, Muhammad Talha Waheed, MBBS, discussed research on the reliability of using recurrence-free survival as an efficacy end point for trials evaluating patients with colorectal cancer peritoneal metastasis.
Read More
Study Finds Susceptibility Gene Variations by Race/Ethnicity in Early-Onset CRC
February 20th 2024In an interview with Targeted Oncology, Andreana N. Holowatyj, PhD, MSCI, discussed data from a study which found racial and ethnic differences in susceptibility genes for early-onset colorectal cancer, suggesting current multigene panel tests may not be accurate for diverse populations.
Read More
