Improving the Treatment of Locally Advanced Pancreatic Cancer
Improving the Treatment of Locally Advanced Pancreatic Cancer
May 2017
- A 64-year-old female was diagnosed with locally advanced pancreatic adenocarcinoma and referred for consultation at a high-volume center
- CT with contrast showed a 2.8-cm mass in the pancreatic body, invading the common hepatic, celiac, and splenic arteries, with abutment more than 180° to the superior mesenteric artery (SMA) but no encasement
- Staging laparoscopy showed no distant metastasis; peritoneal washing cytology showed no malignant cells
- She received FOLFIRINOX followed by capecitabine and concurrent RT
December 2017
- Six months after the initial treatment, the tumor size had decreased to 1.2 cm, and abutment to the main artery was diminished but still detectable
- She underwent distal pancreatectomy with celiac artery resection
- Histopathology showed fibrous changes around the celiac artery; Evans grade IIb
- No evidence of residual tumor at the periphery; R0
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