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Breast Cancer Case Studies

Case Studies: HER2+ Early-Stage Breast Cancer with Ruth O'Regan, MD

Ruth O’Regan, MD, reviews the goals of therapy and treatment options in HER2+ early-stage breast cancer, including neoadjuvant therapy, using case-based scenarios.

HER2+ Early-Stage Breast Cancer with Ruth O'Regan, MD Case 1

Case Scenario 1:

  • This is a post-menopausal 58-year-old female in whom a mass was discovered in her right breast during her annual mammography.
  • Her gynecologist referred her to a breast surgeon; results of her biopsy revealed 3 cm ductal carcinoma
  • Pathology shows: ER– & PR–, HER2 IHC 3+
  • Clinical staging; T2aN1M0
  • Her surgeon discussed the patient’s case at the Breast Tumor Board and it was suggested that the patient be referred to a medical oncologist for consideration of HER2-targeted neoadjuvant therapy.
  • The surgeon shared his opinion with the patient who agreed to go to the medical oncologist to discuss her options.
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