ONCAlert | 2018 ASCO Annual Meeting
Colorectal Cancer Case Studies

Case Studies: Metastatic CRC with Marwan G. Fakih, MD and Tanios Bekaii-Saab, MD

Beverly C. is a 73-year-old retired nurse originally from Albany, New York. She and her husband enjoy golf and traveling.

Metastatic CRC with Marwan G. Fakih, MD and Tanios Bekaii-Saab, MD: Case 2

CASE 2: Metastatic Colorectal Cancer (CRC)

Beverly C. is a 73-year-old retired nurse originally from Albany, New York. She and her husband enjoy golf and traveling.
  • Her prior medical history is notable for type 2 diabetes mellitus and basal cell carcinoma of the neck, successfully excised in 2009
In 2010, routine colonoscopy revealed a large adenomatous polyp that was subsequently removed endoscopically.
  • Patient was advised to return for regular evaluation but subsequently relocated to Florida and was lost to follow-up
In January of 2014, she presented to her PCP with symptoms of irregular bowel movements, fatigue, and unexplained weight loss.
  • CT scan revealed a large mass in the sigmoid colon and multiple hepatic lesions
  • Patient was eventually diagnosed with stage IV colorectal cancer with metastasis to the liver
  • She underwent resection of the sigmoid mass followed by FOLFOX for metastatic disease
  • After 6 months she developed stage 3 sensory neuropathy and oxaliplatin was discontinued; at that time, hepatic lesions were stable
  • She is now continuing treatment with 5-FU and leucovorin until disease progression
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