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Cutaneous Squamous Cell Carcinoma Case Studies

Case Studies: Management of a Patient With a Very Large Ocular CSCC Tumor

Anna C. Pavlick, DO, explains the rationale for treating a 64-year-old woman with a very aggressive case of cutaneous squamous cell carcinoma (CSCC) with a newly-approved systemic therapy option over older, conventional treatment strategies.

Management of a Patient With a Very Large Ocular CSCC Tumor

A 64-Year-Old Woman With Very Large Ocular CSCC Tumor

  • History
    • A 64-year-old woman was referred for a left lower eyelid lesion that was rapidly increasing in size. She complained of intermittent twitching and numbness in the area. She reported that the lesion started on the lower eyelid.
    • PMH: stent placed 10 years ago; hyperlipidemia, well controlled on simvastatin; hypertension, well controlled on metoprolol; rheumatoid arthritis
  • PE
    • Ulcerated lesion, approximately 8-mm in diameter
    • ECOG PS 1
  • Imaging confirmed perineural, vascular, and bone invasion
  • Biopsy confirmed cutaneous squamous cell carcinoma, poorly-differentiated, Clark level V, perineural invasion, vascular invasion
  • Stage: T3N0M0
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