A Case of Recurrent Ovarian Cancer

Video

A Case of Recurrent Ovarian Cancer

December 2016

  • A 38-year old female presented with bloating and pain
  • PMH: unremarkable
  • FH: no malignancy
  • Abdominal/pelvic CT scan: pelvic mass (9-cm) arising from the right ovary, omental cake (15-cm), and extensive peritoneal carcinomatosis
  • CA-125: 1027 U/mL
  • The patient was diagnosed with stage IIIC epithelial ovarian cancer
  • She underwent hysterectomy, bilateral salpingo-oophorectomy, and omentectomy
    • Scattered residual peritoneal nodules (<1 cm) remained following surgery
  • Following surgery, treated with 6 cycles of IP/IV carboplatin/paclitaxel
    • After 6 cycles of therapy, CA-125 level declined to 2.5 U/mL
    • Symptoms were ameliorated

March 2017

  • Patient reported bloating and abdominal pain
  • Lab results showed elevated CA 125 (985 U/mL)
  • CT scan confirmed recurrence with ascites and visible disease (2-cm peritoneal mass)
  • She was treated with bevacizumab and topotecan for 4 cycles
    • Patient had good response therapy
    • After 4 cycles, she was switched to bevacizumab maintenance

October 2017

  • Patient returned with complaint of abdominal pain
  • CT scan revealed ascites and several 1- to 2-cm peritoneal masses in the pelvis and upper abdomen

Related Videos
Video 3 - "Managing Toxicities and Adverse Reactions in HR+/Her2-Low mBC Therapies"
Video 2 - "EMERALD: Underscoring Key Elacestrant Data + Subgroup Analyses for Informed Therapy Selection"
Video 1 - "A 62-Year-Old Woman with HR+ HER2-low Metastatic Breast Cancer and Lung, Liver, and Bone Metastases and Using Biomarker Testing to Guide Treatment Selection"
John Mascarenhas, MD, an expert on myelofibrosis
John Mascarenhas, MD, an expert on myelofibrosis
Related Content