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Lung Cancer Case Studies

Case Studies: EGFR Testing for Metastatic Non-Small Cell Lung Cancer with Jonathan W. Riess, MD, MS

Jonathan Riess, MD, MS, provides practical information on the use of Molecular testing in EGFR lung cancer.

EGFR Testing for Metastatic Non-Small Cell Lung Cancer with Jonathan W. Riess, MD, MS: Case 2

Riess case 2:

A 73-year-old woman with progressing EGFR+ adenocarcinoma.

  • A 73-year-old woman diagnosed with stage IV adenocarcinoma
  • Based on her EGFR+ status, she was treated with erlotinib
  • After 9 months her disease progressed, along with the presence of minor symptoms
  • Tissue biopsy was impeded by the tumor’s location; therefore, cell-free DNA testing was ordered
  • Based on the positive results for a T790M mutation, the patient was switched to osimertinib.
  • Her disease continues to be well-controlled on second-line therapy
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