Stage IIIA Unresectable NSCLC After Chemoradiotherapy

Video

Stage IIIA Unresectable NSCLC After Chemoradiotherapy

Case: A 52-Year-Old Male With Stage IIIA NSCLC

Initial presentation

  • A 52-year-old man presented with a 15-lb weight loss and worsening dyspnea
  • PMH: HTN
  • SH: Computer programmer; Smoked a pack/day for 30 years; Quit smoking 2 years ago; Married with 4 kids
  • PE: Unremarkable

Clinical workup

  • Imaging:
    • Initial CT showed a 5-cm left upper lobe mass with aortopulmonary window and left paratracheal adenopathy measuring up to 2.5 cm
    • Subsequent PET scan showed activity in the left upper lobe mass and all nodal areas
    • No extrathoracic disease was identified
    • MRI showed no brain metastases
  • Mediastinal sampling: EBUS was performed and documented squamous carcinoma in the left paratracheal lymph nodes
  • Staging: T2N2M0
  • ECOG PS 1
  • Multidisciplinary tumor board deemed his tumor unresectable due to multistation N2 disease

Treatment

  • Concurrent cisplatin/etoposide with external-beam radiotherapy
  • Repeat CT 4 weeks after completion of concurrent chemoradiotherapy showed a PR with no new sites of disease
Related Videos
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Related Content