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Lung Cancer Case Studies

Case Studies: Treatment of ALK+ Non-Small Cell Lung Cancer

In this case-based interview, David Spigel, MD, discusses the treatment of a patient who develops ALK+ non–small cell lung cancer.

Treatment of ALK+ Non-Small Cell Lung Cancer

  • A 62-year-old female never-smoker presented with dyspnea, cough and fatigue. 
  • Patient has a performance status of 1 due to the decrease in her daily activities.
  • Chest X-ray showed multiple bilateral lung nodules.
  • PET/CT showed left adrenal metastases.
  • Brain MRI was negative.
  • Bronchoscopy was performed with a fine needle aspirate biopsy. 
  • Pathology results showed moderately differentiated adenocarcinoma.
  • Molecular testing showed ALK-rearrangement.
  • Patient was started on ceritinib.
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