ONCAlert | Upfront Therapy for mRCC

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In a recent review of the 5-year outcomes from the COMBI-d and COMBI-v trials published in the New England Journal of Medicine, investigators saw long-term benefit with the use of dabrafenib plus trametinib as first-line treatment in about one-third of patients with unresectable or metastatic melanoma and BRAF V600E or V600K mutations.

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