Thomas W. Flaig, MD, discusses the most dramatic change in the treatment landscape for patients with advanced bladder cancer. Over the last several years, 5 checkpoint inhibitors have been approved in this space.
Thomas W. Flaig, MD, professor and associate dean for clinical research, Genitourinary Cancer Program, Division of Medical Oncology, University of Colorado, discusses the most dramatic change in the treatment landscape for patients with advanced bladder cancer. Over the last several years, 5 checkpoint inhibitors have been approved in this space.
Checkpoint inhibitors are leading to response rates in the 20% to 25% range as monotherapy. Flaig says he would like to see higher response rates. Both patients and providers want durable responses that are well tolerated, and checkpoint inhibitors appear promising in that respect.
FDA Accepts IND for UGN-103 in Low-Grade Intermediate-Risk NMIBC
April 15th 2024An investigational new drug application for UGN-103 was accepted by the FDA. A phase 3 study to assess the safety and efficacy of the agent in low-grade intermediate-risk non-muscle invasive bladder cancer is anticipated.
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