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Immunotherapy Enters the Treatment Landscape for Cervical Cancer

Krishnansu S. Tewari, MD
Published Online:3:53 PM, Wed October 10, 2018

Krishnansu S. Tewari, MD, associate professor, Division of Gynecologic Oncology, Department of Obstetrics & Gynecology, University of California, Irvine, discusses the excitement around immunotherapy in cervical cancer. 

Scientifically, it makes sense to look at these therapies in this setting, Tewari says. The mutational burden of cervical cancer is similar to other solid tumors where immunotherapy has had positive results, according to phase III findings. 

Similar tumor clusters in certain lung cancers and head and neck cancers have shown a signal for immunotherapy, especially with checkpoint inhibition. Cemiplimab (Libtayo), an anti-PD-1 agent, is now under investigation in patients with cervical cancer.
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