Cathy Eng, MD, FACP, professor, Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, discusses ongoing clinical trials in the <em>BRAF</em>-mutant colorectal cancer patient population.
Cathy Eng, MD, FACP, professor, Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, discusses ongoing clinical trials in theBRAF-mutant colorectal cancer patient population.
The most recent study presented for theBRAF-mutant population was SWOG S1406, which looked at a control arm of irinotecan and cetuximab with or without vemurafenib inBRAF-mutant metastatic colorectal cancer. The study was positive for progression-free survival, which was the primary endpoint.
Eng believes this was an eye-opening study in that it suggests testing patients for the presence of aBRAFmutation and providing patients with a BRAF inhibitor.
Retrospective Data Demonstrates Efficacy of Regorafenib in mCRC
April 16th 2024During a Case-Based Roundtable® event, Madappa Kundranda, MD, PhD, discussed recent retrospective studies that compared outcomes between the available treatment options in patients with relapsed/refractory advanced colorectal cancer in the first article of a 2-part series.
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