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Ongoing Research for New Frontline Treatments in Follicular Lymphoma

Carla Casulo, MD
Published Online:2:04 PM, Wed March 20, 2019


Carla Casulo, MD, associate professor in the department of medicine at the University of Rochester Medical Center, discusses recent research for new frontline options for patients with newly diagnosed follicular lymphoma (FL).

A large randomized study looked at frontline treatment with the combination lenalidomide (Revlimid) plus rituximab (Rituxan) compared to standard chemotherapy. The study aimed to establish non-inferiority, but it was found that the 2 regimens were not dramatically different, says Casulo.

Casulo notes an improvement in outcomes, but says these data are not going to change the general practice too much. New treatments for patients with FL at the time of diagnosis is still an area that is actively being explored.
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