A 56-Year-Old Female With Recurrent Ovarian Cancer

Video

A 56-Year-Old Female With Recurrent Ovarian Cancer

Case: A 56-Year-Old Female With Recurrent Ovarian Cancer

  • 56-year-old female diagnosed with stage IV ovarian cancer (2016)
    • Weight: 105-lb, height: 5’6”, BMI of 16.9
    • Pathology: high-grade serous carcinoma, epithelial ovarian cancer
    • CA-125: 475 U/mL
    • CT with contrast of the pelvis, abdomen, and chest revealed a 3.5-cm mass in the right ovary and peritoneal carcinomatosis
    • Patient underwent suboptimal debulking surgery; residual disease 1.5 cm
    • Received IV/IP carboplatin/paclitaxel (6 cycles); achieved complete response
  • 1 year later (2017) symptoms returned; CA-125, 265 U/mL; ECOG: 1
    • Received carboplatin/paclitaxel (6 cycles) and bevacizumab; achieved good partial response; CA-125, 45 U/mL; continued on bevacizumab maintenance
  • 8 months following second-line therapy (2018), again presented with symptoms; CA-125, 550 U/mL; ECOG: 0
    • Received carboplatin/gemcitabine (6 cycles); CA-125, 54 U/mL; achieved complete response
  • Currently:
    • CA-125, 585 U/mL
    • CT shows 2.7 cm right lower lobe lung mass
    • ECOG: 0
Related Videos
Video 3 - "Managing Toxicities and Adverse Reactions in HR+/Her2-Low mBC Therapies"
Video 2 - "EMERALD: Underscoring Key Elacestrant Data + Subgroup Analyses for Informed Therapy Selection"
Video 1 - "A 62-Year-Old Woman with HR+ HER2-low Metastatic Breast Cancer and Lung, Liver, and Bone Metastases and Using Biomarker Testing to Guide Treatment Selection"
John Mascarenhas, MD, an expert on myelofibrosis
John Mascarenhas, MD, an expert on myelofibrosis
Related Content