Frontline Treatment Options for Hodgkin's Lymphoma
Frontline Treatment Options for Hodgkin's Lymphoma
A 32-Year-Old Man with Stage IV Hodgkin's Lymphoma
- History & Physical:
- A 32-year-old man presented to his PCP in January 2017 complaining of abdominal pain, pruritus, fevers of over 101⁰ F, and weight loss
- Imaging
- PET scan showed avid mediastinal mass
- Labs
- HgB 12.2 g/dL
- WBC 7,500 mm2
- ALC 3,200 mm2
- Albumin 3.9 mg/dL
- ANC 4,200/mm3
- Liver and renal function tests WNL
- Biopsy confirmed mixed cellularity classical Hodgkin’s lymphoma (HL)
- Normal lung and cardiac function
- Final Staging: Stage IVB, cHL, IPS score 2
- ECOG PS 2
- He received 2 cycles of ABVD. PET/CT restaging showed Deauville (1-). He received 4 additional cycles of AVD
- He achieved a CR
- 2 years after completion of therapy, the patient complained of a persistent cough and fatigue
- PET/CT showed bilateral mediastinal masses
- Biopsy confirmed cHL
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