Metastatic Cutaneous Squamous Cell Carcinoma

Video

Metastatic Cutaneous Squamous Cell Carcinoma

Case: A 79-Year-Old Male With Metastatic CSCC

April 2016

  • A 79-year-old male presented to dermatologist with a large ulcerative lesion on clavicle; he reported lesion first appeared 5 months ago while living in Florida for the winter
  • Diagnosed with localized cutaneous squamous cell carcinoma
  • Standard surgical excision performed with 4 mm clinical margins; postoperative margins negative

May 2018

  • Patient returns to dermatologist for follow-up c/o multiple lesions on shoulder and neck around the site of prior excision
  • PE:
    • Multiple visible, ulcerated lesions, approximately 2-3cm in diameter; suspected tumor depth >5mm
    • Multiple palpable nodes ~2cm
  • Imaging confirmed 7 mm invasion into subcutaneous fat; parotid nodal involvement
  • Biopsy confirmed cutaneous squamous cell carcinoma, poorly-differentiated
  • Diagnosis: Metastatic cutaneous squamous cell carcinoma
  • Stage IV: T3N2M0
  • Patient started on cemiplimab
Related Videos
Video 3 - "Managing Toxicities and Adverse Reactions in HR+/Her2-Low mBC Therapies"
Video 2 - "EMERALD: Underscoring Key Elacestrant Data + Subgroup Analyses for Informed Therapy Selection"
Video 1 - "A 62-Year-Old Woman with HR+ HER2-low Metastatic Breast Cancer and Lung, Liver, and Bone Metastases and Using Biomarker Testing to Guide Treatment Selection"
John Mascarenhas, MD, an expert on myelofibrosis
John Mascarenhas, MD, an expert on myelofibrosis
John Mascarenhas, MD, an expert on myelofibrosis
Related Content