Treating Chronic Lymphocytic Leukemia in Elderly Patients

Video

Treating Chronic Lymphocytic Leukemia in Elderly Patients

  • A 76-year-old male presented with symptoms of low-grade fever, (101.1oF) chills, and weight loss. The patient feels severely fatigued and required extensive rest. He was recently hospitalized for pneumonia.
  • PMH: Hypertension controlled on candesartan, diabetes managed with metformin
  • PE: Pallor and is weak-appearing, vital signs WNL, enlarged mobile lymph nodes bilaterally (~2.0 cm), anterior cervical chain, no hepatosplenomegaly
  • PS, ECOG 2
  • Laboratory findings:
    • WBC; 18.5 X 109/L, 65% lymphocytes
    • Lymphocytes; 86.2 X 109/L
    • Hb; 12.2 g/dL
    • Platelets; 305 X 109/L
    • ANC; 120/mm3
  • Flow cytometry; CD5+, CD19+, CD23+, CD38-low,
  • Cytogenetics, IgVH mutation status, unknown
  • β2M, 2.6 mg/L
  • BM biopsy; 50% lymphocytes
  • Diagnosis; chronic lymphocytic leukemia
  • The patient was treated with ibrutinib and achieved a complete response to therapy after 2 months
Related Videos
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Related Content