Preliminary Workup for Signs of Recurrent Melanoma

May 12, 2017

A 46-year-old Caucasian female presented one year ago with deep ulcerated primary tumor and multiple involved lymph nodes.
She was diagnosed with stage IIIC melanoma.
Patient underwent wide local incision and compete lymph node dissection and appeared to be clear of disease.
Patient decided not to pursue adjuvant therapy after surgery.
Six months after surgery, she developed abdominal pain.
Imaging showed multiple masses in the liver, > 1 cm, scattered pulmonary nodules and some enlarged lymph nodes.
Tumor biopsy confirmed melanoma and mutational analysis showed BRAF V600E mutation.
The patient is started on dabrafenib 150 mg bid and trametinib 2 mg qd.