EGFR+ NSCLC

Video

EGFR+ NSCLC

December 2017

  • A 66-year-old Asian woman presents to her PCP complaining of visual disturbances, nausea, fatigue, and sporadic headaches
  • History: HTN, managed on candesartan; hyperlipidemia managed on simvastatin; no smoking history
  • PE: BP, 148/70; LLL auscultation reveals decreased breath sounds
  • CBC: WNL
  • Imaging studies:
    • MRI of the head demonstrated a right parietal mass at the gray—white junction with vasogenic edema
    • CT of chest, abdomen, and pelvis revealed a 3.4-cm mass in the left lower lobe, and several small liver nodules
  • CT-guided transthoracic needle biopsy of the lung lesion showed grade 2 adenocarcinoma, acinar
  • Molecular testing: EGFR exon 19 deletion
  • Staging: T2aN0M1c
  • ECOG 1
  • The patient was started on osimertinib 80 mg once daily
Related Videos
Video 3 - "Managing Toxicities and Adverse Reactions in HR+/Her2-Low mBC Therapies"
Video 2 - "EMERALD: Underscoring Key Elacestrant Data + Subgroup Analyses for Informed Therapy Selection"
Video 1 - "A 62-Year-Old Woman with HR+ HER2-low Metastatic Breast Cancer and Lung, Liver, and Bone Metastases and Using Biomarker Testing to Guide Treatment Selection"
John Mascarenhas, MD, an expert on myelofibrosis
John Mascarenhas, MD, an expert on myelofibrosis
John Mascarenhas, MD, an expert on myelofibrosis
John Mascarenhas, MD, an expert on myelofibrosis
Related Content