Relapsed/Refractory Multiple Myeloma

Video

Relapsed/Refractory Multiple Myeloma

Case: 75-Year-Old Man With Symptomatic R/R Multiple Myeloma

January 2015

  • A 75-year-old man was diagnosed with multiple myeloma; R-ISS stage I
  • PMH: hypertension; coronary artery disease post stent placement
  • Patient was treated with lenalidomide + dexamethasone for 9 months; transplant-ineligible due to age and performance status
  • Patient achieved a VGPR, discontinued treatment thereafter due to patient request

September 2018

  • On routine follow-up 3 years later, patient presents with new-onset back pain and generalized fatigue
  • Imaging: multiple new lytic lesions with compression fractures
  • Laboratory results:
    • Hb, 10.7 g/dL
    • Ca2+, 9.3 mg/dL
    • Creatinine, 1.1 mg/dL
    • M-protein, 3.2 g/dL
  • Cytogenetics/FISH: del (17p) discovered at relapse
  • ECOG PS: 2
Related Videos
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Stephen T. Oh, MD, PhD, an expert on myelofibrosis
Related Content