Risk/Benefits of Managing AEs with Combination Therapy
Dr. Motzer discusses the risk/benefits considerations that guide decisions around continuing combination therapy with dose adjustments or stopping one agent when moderate AEs like diarrhea or liver enzyme elevations emerge in nccRCC patients on IO plus TKI regimens.
EP: 1.Initial Impression of Case
EP: 2.Appropriateness of Initial Therapy
EP: 3.Efficacy and safety of KEYNOTE-427
EP: 4.Efficacy and Safety and Emerging Combinations
EP: 5.Efficacy of Combination vs Single Agent Therapy
EP: 6.Managing Adverse Events
EP: 7.Risk/Benefits of Managing AEs with Combination Therapy
EP: 8.Quality of Life Preservation
EP: 9.Future Management of nccRCC
FDA Accepts BLA for Subcutaneous Nivolumab Across Various Solid Tumors
May 6th 2024The FDA is considering a subcutaneous nivolumab formulation for various solid tumors based on promising data from the phase 3 CheckMate -67T trial. A target action date has been set for February 28, 2025.
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Sustained Treatment-Free Survival in RCC Seen With Nivolumab and Ipilimumab
April 30th 2024Nivolumab monotherapy plus salvage nivolumab/ipilimumab demonstrated superior treatment-free survival rates among patients with advanced renal cell carcinoma, especially in patients with favorable risk profiles.
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