Provenge in Combination with Radium-223
Oliver Sartor, MD, board professor, cancer research, Tulane University, discusses a trial that would study Provenge (sipuleucel-T) in combination with radium-223 as a potential treatment option for patients with prostate cancer.
Oliver Sartor, MD, board professor, cancer research, Tulane University, discusses a trial that would study Provenge (sipuleucel-T) in combination with radium-223 as a potential treatment option for patients with prostate cancer.
Clinical Pearls:
- Both companies that developed the drugs have approved a trial design
- The trial will be small and have immunologic endpoints to help physicians better understand the mechanisms of action behind combining radiation therapy and immunotherapy
- Researchers hypothesize that radiation may be able to induce epitopes that can trigger better immune responses
- There is good preclinical data that suggests that radiation and immunotherapy may have interesting interplay
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May 13th 2024In an interview with Targeted Oncology for Brain Cancer Awareness Month, Theodore Schwartz, MD, discussed the challenges of targeting brain tumors, emerging therapies, and strategies to overcome the blood-brain barrier.
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FPI-2265 Dosing Commences in Phase 2 AlphaBreak Trial for mCRPC
May 10th 2024The first patient has been dosed in the phase 2 AlphaBreak trial with FPI-2265 for the treatment of metastatic castration-resistant prostate cancer, marking a significant milestone in advanced cancer treatment.
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