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Top Medical News Today

Daily Physical Activity Shown to Improve Outcomes in mCRC
Engaging in moderate physical activity daily was shown to reduce mortality and cancer progression in patients with metastatic colorectal cancer.
Surgical Palliation Maintains QOL, Improves Food Intake in Advanced Gastric Cancer
Patients with malignant gastric outlet obstruction who received surgical palliation maintained their quality of life and improved solid food intake for at least 3 months after surgery.
Pembrolizumab/Ramucirumab Combo Active in Advanced Gastric/GEJ Adenocarcinoma
A novel combination regimen of ramucirumab plus pembrolizumab demonstrated modest activity in patients with previously treated gastric or gastroesophageal juncture cancer.
Ian Chau, MD, discusses interim safety and clinical activity results in patients with advanced gastric or gastroesophageal junction adenocarcinoma from a multi-cohort phase I study of ramucirumab plus pembrolizumab.
Lenvatinib Regimen Setting Pace for Emerging Combos in Kidney Cancer
Thomas E. Hutson, DO, PharmD, discusses the power of the lenvatinib/everolimus combination and how and when the regimen should be used in patients with advanced renal cell carcinoma. 
Ibrutinib Granted Accelerated Approval by FDA for Marginal Zone Lymphoma
The FDA has granted an accelerated approval to ibrutinib as a treatment for patients who require systemic therapy with marginal zone lymphoma following at least one prior anti-CD20-based therapy.
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Rucaparib Approved by FDA for Treatment of BRCA-Positive Ovarian Cancer
Rucaparib Approved by FDA for Treatment of BRCA-Positive Ovarian Cancer
The FDA has approved rucaparib (Rubraca) as a treatment for patients with BRCA-positive advanced ovarian cancer who have received at least 2 prior lines of chemotherapy.
Wierda Discusses Current Questions in Frontline CLL Treatment
William G. Wierda, MD, PhD, discusses which groups of CLL patients may benefit from ibrutinib versus chemoimmunotherapy and clinical trials that may provide further clarification.
Blinatumomab Receives FDA Approval for Acute Lymphoblastic Leukemia
Blinatumomab (Blincyto) has received accelerated approval from the FDA for the treatment of pediatric and adolescent patients with Philadelphia chromosome-negative (Ph-) relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL).
NDA for Neratinib in HER2-Positive Breast Cancer Accepted by FDA
A new drug application (NDA) for neratinib as an extended adjuvant therapy for patients with HER2-positive breast cancer following prior treatment with postoperative trastuzumab (Herceptin) has been accepted by the FDA
FDA Gives Niraparib Fast Track Designation for Ovarian Cancer
Niraparib has been granted a fast track designation by the FDA as a treatment for women with recurrent platinum-sensitive ovarian, fallopian tube, or primary peritoneal cancer