May 9th 2024
During a Case-Based Roundtable® event, Madappa Kundranda, MD, PhD, discussed recent retrospective studies that looked at outcomes of dose optimization of regorafenib for patients with relapsed/refractory advanced colorectal cancer in the first article of a 2-part series.
Community Practice Connections™: Real-World Applications of Novel Therapies Across TNBC and Addressing Disparities in Care
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6th Annual Precision Medicine Symposium: An Illustrated Tumor Board
October 18-19, 2024
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Advances in TNBC: Communicating with Your Patients About Clinical Trial Awareness and Treatment Concerns to Improve Clinical Outcomes
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Community Practice Connections™: 5th Annual Precision Medicine Symposium – An Illustrated Tumor Board
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41st Annual CFS®: Innovative Cancer Therapy for Tomorrow
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Molecular Characterization Plays Vital Role in Selecting Optimal Colon Cancer Treatment
November 2nd 2018Al B. Benson III, MD, FACP, FASCO, discusses the treatment landscape for advanced and metastatic CRC and how molecular profiling can play a vital role in selecting the optimal treatment plan for each patient. He also emphasizes the importance of participation in clinical trials to further understand these patients.
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Despite Advances, Interpreting Data From Genomics and Precision Medicine Lags
October 25th 2018I think one of the most important advancements in biomedical technology that has improved our understanding of the complexities of cancer is the ability to sequence the cancer genome for any individual patient, in a rapid and cost-effective manner, to help us make treatment decisions in the clinic.
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Financial Advocacy Grows Under the Value-Based System
October 24th 2018Groundbreaking developments in cancer therapies can change lives, extending survival and sending patients who previously thought their chances were slim into remission. But these therapies come at a cost, and many patients reel at the prospect of heavy financial burdens. To help patients and programs meet the challenges of affording cancer treatments, community cancer centers are expanding the role of financial advocates in their organizations.
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ACCC President Reignites Resilience in Oncology Caregivers
October 23rd 2018Thomas A. Gallo, MS, MDA, president of the Association of Community Cancer Centers, discusses his mission as president to “reflect, renew, and reignite” in order to create a more resilient oncology team for the community.
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Entrectinib Induces Responses Across Multiple Tumor Types
October 22nd 2018Among patients with advanced solid tumors associated with <em>NTRK</em> gene fusions, more than half had responses to the small-molecule inhibitor entrectinib, according to an integrated analysis of 3 clinical trials presented at the 2018 ESMO Annual Congress.
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Larotrectinib Induces 80% ORR in Advanced NTRK+ Solid Tumors
October 22nd 2018Larotrectinib induced an objective response rate of 80% in patients with advanced solid tumors who harbored <em>NTRK </em>gene fusions, according to results pooled from 3 small trials of the TRK inhibitor. Results were presented during the 2018 ESMO Congress.
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CMS Tackles Drug Prices, But What Does This Mean for Patient Care Access?
October 19th 2018Rising prescription drug prices continue to add to the burden of paying for quality healthcare. In an effort to confront such costs, the Centers for Medicare & Medicaid Services has rescinded a prohibition on step therapy for Medicare Advantage plans. But some contend such a policy will reduce patient access to optimal medication.
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Grothey Discusses Evolving Treatment Options for Colon Cancer
October 12th 2018Axel Grothey, MD, recently shared the treatment considerations and decisions he makes when treating patients with colon cancer. Grothey, a medical oncologist at the West Cancer Center, explained how he would treat these patients based on case scenarios during a <em>Targeted Oncology</em> live case-based peer perspectives presentation.
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Pontchartrain Cancer Center Pushes Limits of Community Care in Southeast Louisiana
September 27th 2018Pontchartrain Cancer Center was founded in 2005 to serve an area of Louisiana that lacked the necessary resources for cancer care. This community cancer center, with 2 locations in Southeast Louisiana, accommodates any patient to walk through its doors, filling a major unmet need for the community in this rural area.
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Georgetown Researcher Joins Colorectal Cancer Alliance as Director of Medical Affairs
September 24th 2018Ronit Yarden, PhD, MHSA, has joined the Colorectal Cancer Alliance as its new director of medical affairs, where she will work to develop the organization’s funding initiatives and act as liaison to its medical scientific advisory committee with the goal of promoting patient education and disease prevention.
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SIRT Added to Chemotherapy Extends Survival in Right-Sided Colorectal Cancers
September 19th 2018Adding selective internal radiation therapy to chemotherapy improved overall survival by 5 months compared with chemotherapy alone for patients with liver-only or liver-dominant right-sided primary metastatic colorectal cancer, according to results from a post hoc analysis of 2 randomized, controlled trials.
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Debating the Standard of Care for Resectable Colorectal Cancer Liver Mets
September 18th 2018Two oncologists from the Winship Cancer Institute of Emory University reviewed data for and against the use of chemotherapy for patients with resectable colorectal cancer liver metastases. Mehmet Akce, MD, spoke in favor of chemotherapy, while Shishir K. Maithel, MD, argued against it.
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Regorafenib Safety, Efficacy in mCRC Confirmed in Published Results
September 12th 2018According to findings from the phase IIIb CONSIGN trial, now published in <em>The Oncologist</em>, safety and efficacy findings for regorafenib in patients with previously treated metastatic colorectal cancer were consistent with previous phase III results.
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Examining Immunotherapy Treatment Options in Colorectal Cancer
August 24th 2018Checkpoint inhibitors have provided practice-changing therapeutic targets for clinicians by regulating host immune response. The treatment landscape in colorectal cancer has significantly changed as a result, but more research is necessary for certain subtypes, particularly the microsatellite stable patient population.
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The Importance of Molecular Testing in CRC
August 22nd 2018Scott Kopetz, MD, PhD, FACP, associate professor, Department of Gastrointestinal Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, discusses the importance of molecular testing in colorectal cancer.
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Biomarker Development Is Key to the Future of Precision Oncology
August 21st 2018No one doubts that molecular testing has rapidly improved care for patients with colorectal cancer, Stanley R. Hamilton, MD, told his audience at the 2nd Annual International Congress on Oncology Pathology.
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Presence of MSI-H, MMR-D Predicts Lynch Syndrome Across Tumor Types
August 16th 2018Results from a prospective study involving 15,045 tumor samples that underwent next-generation sequencing using MSK-IMPACT and microsatellite-instability testing demonstrate that MSI-high and DNA mismatch-repair deficient tumors are predictive of Lynch syndrome across all tumor types. The results suggest that LS-associated cancers may be more heterogeneous than previously suspected.
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