FYB206 is being reviewed as a pembrolizumab biosimilar after meeting pharmacokinetic equivalence; no additional efficacy trial is required.
|Articles|October 1, 2014
A Phase Ib Study of Pembrolizumab in Bladder Cancer
Author(s)Elizabeth Plimack, MD, MS
Elizabeth Plimack, MD, MS, director, Genitourinary Clinical Research, Fox Chase Cancer Center, discusses a phase Ib study of pembrolizumab for the treatment of patients with bladder cancer.
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Clinical Pearls
Elizabeth Plimack, MD, MS, director, Genitourinary Clinical Research, Fox Chase Cancer Center, discusses a phase Ib study of pembrolizumab for the treatment of patients with bladder cancer.
- 33 patients with urothelial tract cancer were enrolled on this trial.
- A subset of patients experienced a decrease in tumor volume. There were 3 complete responses.
- Overall survival data seen in this study were at the top bound of historical data.
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