Head & Neck Cancers | Clinical

FDA Grants Priority Review to Toripalimab +/- Chemotherapy in Advanced NPC

November 01, 2021

The biologics license application for toripalimab will undergo a speedy review by the FDA for consideration as a frontline treatment option for patients with advanced recurrent or metastatic nasopharyngeal carcinoma in combination with gemcitabine and cisplatin, and as a single-agent for the second-line or above treatment of recurrent or metastatic disease after platinum-containing chemotherapy.

NBTXR3 With or Without I/O Shows Survival Benefit in Locally Advanced HNSCC

October 28, 2021

NBTXR3, which is activated by radiotherapy, was found to be safe and tolerable in frail patients with head and neck squamous cell carcinoma. The agent can be used on its own or in combination with other immunotherapy agents.

Early-Phase Targeted Agents Are Poised to Expand Armamentarium in HNSCC

September 23, 2021

The emergence of early-phase immune-oncology agents and their respective novel mechanisms of action in head and neck squamous cell carcinoma suggests a new standard of care in the metastatic first-line setting within the next 2 years.