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ACVR1 Inhibition With Pacritinib Leads to Anemia Improvement in MF
ACVR1 Inhibition With Pacritinib Leads to Anemia Improvement in MF

November 29th 2023

Based on in vitro data, pacritinib led to a 4-fold higher potency for inhibition of the hepcidin regulator ACVR1 vs momelotinib among patients with cytopenic myelofibrosis and led to an increase in red blood cell transfusion independence.

Oh Discusses Goals of Treatment in Patients With Cytopenic Myelofibrosis
Oh Discusses Goals of Treatment in Patients With Cytopenic Myelofibrosis

November 23rd 2023

Trials Support Use of Momelotinib After JAK Inhibition for Anemic MF
Trials Support Use of Momelotinib After JAK Inhibition for Anemic MF

November 21st 2023

MANIFEST-2 Meets Primary End Point With Pelabresib Plus Ruxolitinib in MF
MANIFEST-2 Meets Primary End Point With Pelabresib Plus Ruxolitinib in MF

November 21st 2023

JAK2 Inhibition’s Role in Newly Diagnosed Myelofibrosis
JAK2 Inhibition’s Role in Newly Diagnosed Myelofibrosis

November 20th 2023

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