Conference Coverage
Trending on Targeted Oncology - Immunotherapy, Biomarkers, and Cancer Pathways
HCB101, Novel Fusion Protein, Earns FDA Orphan Drug Status in Gastric Cancer
FDA Accepts NDA for Iberdomide-Based Regimen in Multiple Myeloma
Addressing Resistance and Rare Subsets in GIST
Landmark Trials Guiding Systemic Therapy in Advanced NETs
Narrowing the Scope: PARP Inhibitor Restrictions in Ovarian Cancer
Latest News
Shorts










Podcasts

Navigating the Future of CLL Care
Experts explore the evolving landscape of chronic lymphocytic leukemia treatment, highlighting targeted therapies, MRD strategies, and future innovations.

Supporting Community Oncologists in a GU Research Era
Explore the vital role of community oncology in GU cancer treatment, bridging research and real-world applications for better patient care.

Gut Health & Myeloma: How Bacteria May Predict Transplant Success With Pooja Phull, MD
A study reveals the gut microbiome's role in predicting multiple myeloma outcomes, highlighting butyrate-producing bacteria as key indicators of patient survival.

Experts Delve Into Organ Preservation for Genitourinary Cancers
Benjamin Garmezy, MD, and Alexander Kenigsberg, MD, discuss strategies for preserving organs in GU cancers in the Treating Together podcast.

Navigating Modern Lung Cancer Treatment and Clinical Trial Access
Edward S. Kim, MD, MBA, and Neel Shah, MD, discuss advancing lung cancer care and tackling real-world access barriers for community physicians in the Treating Together podcast.

Advancing Prostate Cancer Treatment With Shared Decision-Making
In our first episode of Treating Together, Benjamin Garmezy, MD, and Ralph J. Miller Jr, MD, discuss multidisciplinary prostate cancer care.

Predicting Palbociclib Outcomes in Breast Cancer Using Deep Learning
Xiaojie Zhang, MD, and Akshat Singhal, PhD, discuss their research leveraging deep learning to predict how patients with ER+/HER2- breast cancer will respond to palbociclib.

BMT CTN 1902 in Myeloma: Key Findings With Garfall
In this episode of Targeted Talks, Alfred L. Garfall, discusses the phase 2 BMT CTN 1902 trial of idecabtagene vicleucel in patients with multiple myeloma.

Exploring Innovations in Lymphoma Treatment With Russler-Germain
David A. Russler-Germain, MD, PhD, discusses his path in oncology and the many advancements shaping lymphoma treatment today.

Behind the FDA Approval of Dato-DXd in HR+/HER2– Breast Cancer With Bardia
In this episode of Targeted Talks, Aditya Bardia, MD, MPH, FASCO, discusses the recent FDA approval of datopotamab deruxtecan in breast cancer.
Videos
All News

Adjuvant selpercatinib boosts event-free survival after surgery in early-stage RET fusion-positive NSCLC, signaling a potential new standard and expanding genomic testing.

Why most eligible lymphoma patients miss CAR T: experts urge stronger academic-community handoffs, clearer protocols, and smarter caregiver support.

During a live event, Hagen Kennecke, MD, discusses how RADIANT-4 and NETTER trials have reshaped NET care with everolimus and PRRT.

How to manage Richter transformation: rapid biopsy, targeted combos, and early referral for CAR T or transplant—closing the access gap.

FDA grants orphan drug designation to HCB101 for gastric cancer; early trials suggest safer CD47 checkpoint blockade with promising tumor control in advanced settings.


ASH Releases New Guidelines for ALL Care in Adolescents and Young Adults
ASH updates AYA ALL care: pediatric-inspired frontline therapy, MRD-driven decisions, targeted TKIs, and immunotherapy-led relapse treatment.

BTK inhibitors or time-limited venetoclax combos? Expert breaks down CLL frontline choices, IGHV and p53 risk, and what fits patient life.

Nivolumab–ipilimumab extends survival in unresectable HCC, but US cost-effectiveness falls short; dosing changes or price cuts may shift value.

Dr Manmeet Ahluwalia on the Precision Oncology Revolution in Brain Metastases
Dr Manmeet Ahluwalia explores how precision oncology and targeted therapies are transforming brain metastases care, extending survival from months to years.

Cancer Breakthroughs for All: The Pursuit of Equitable Oncology Innovation
Cancer breakthroughs surge, but trials and novel therapies stay out of reach for many. See how community care, policy, and design can close gaps.

Prostate Cancer Living Guidelines Establish Frontline Combinations

A novel blood based surveillance test using artificial intelligence and next-generation sequencing identified relapse a median of 41 days before clinical detection in patients with AML or MDS following transplant.

Cabozantinib plus temozolomide led to favorable short-term progression-free survival in a single-arm trial of patients with advanced leiomyosarcoma.

FDA Accepts sNDA for Photodynamic Therapy in Superficial Basal Cell Carcinoma
FDA accepts Ameluz PDT sNDA for superficial basal cell carcinoma, with strong phase 3 clearance data and a September 2026 decision deadline.

Tumor Treating Fields Therapy Garners FDA Approval in Locally Advanced Pancreatic Cancer
FDA approves Optune Pax, a wearable tumor treating fields device, to pair with GnP chemo in locally advanced pancreatic cancer, extending survival and delaying pain.

G6PD deficiency links to higher remission and longer survival in AML patients on venetoclax plus azacitidine, suggesting a simple biomarker to guide treatment.

Phase 3 SIGMA Trial of Safusidenib Is Initiated for IDH1-Mutant Glioma
Global phase 3 trial tests safusidenib maintenance after chemoradiotherapy, aiming to delay recurrence and improve survival in IDH1-mutant astrocytoma.

FDA fast-tracks irpagratinib for FGF19+ advanced liver cancer, with early trials showing strong response rates and ongoing combo study momentum.

A recent white paper determines that the link between GLP-1 agonist inhibitors and thyroid cancer is unconvincing.

FDA RMAT boosts inhaled gene therapy KB707, delivering IL‑2/IL‑12 to lung tumors; early trial shows responses with manageable safety.

Brittany Dulmage, MD, discusses why a popular ingredient in hair, skin, and nails vitamins may not be a safe option for patients undergoing cancer treatment.

FDA approves pembrolizumab with chemotherapy for platinum-resistant ovarian cancer, showing significant survival benefits in clinical trials.

Final MOUNTAINEER data show tucatinib plus trastuzumab delivers durable responses and manageable safety in HER2+ RAS wild-type metastatic colorectal cancer.

NPX372 received Investigational New Drug Clearance from the FDA, allowing for clinical development.

Preliminary Gintemetostat Outcomes Draw Attention to t(4;14) in R/R MM
In an interview, Saad Z. Usmani, MD, MBA, discussed the significance of phase 1 outcomes of gintemetostat therapy for patients with heavily pretreated multiple myeloma.

New research defines distinct therapeutic strategies for the 2 classes of CALR mutations in myelofibrosis, with implications for future patient management and clinical trial design.

SEER-Medicare data show just 4% of older adults with blood cancers enter clinical trials, revealing disparities and fixable access barriers.

At 33.6 months' follow-up, patients with standard-risk multiple myeloma had improved progression-free survival outcomes with cilta-cel vs standard-of-care.

A retrospective study of tumor-infiltrating lymphocyte therapy showed that despite its benefit, many patients were unable to receive lifileucel.

T-Cell Therapy EB103 Demonstrates Safety in B-Cell Non-Hodgkin Lymphoma
Phase 1 data show EB103 delivers 100% complete responses at high dose with manageable toxicity, offering a safer, durable option for high-risk B-cell NHL.

Post hoc data suggest Orca-T may boost survival and cut non-relapse mortality after allogeneic stem cell transplant in MDS and leukemias, pending phase 3 validation.

FDA Approves Label Update for Axi-Cel for R/R Primary CNS Lymphoma
FDA lifts Yescarta limits for relapsed primary CNS lymphoma, expanding CAR T access with phase 1 safety data—what to know about neuro risks.









































