MPNs | Clinical

Luspatercept Demonstrates Efficacy and Tolerable Safety in Patients With MDS/MPN-RS-T

December 07, 2020

Luspatercept demonstrated clinical efficacy and a tolerable safety profile in patients with myelodysplastic syndrome/myeloproliferative neoplasms with ring sideroblasts and thrombocytosis who were enrolled in the MEDALIST trial.

The Role of JAK Inhibitors Continues to Evolve to Improve Outcomes in Myelofibrosis

November 10, 2020

In an interview with Targeted Oncology, John O. Mascarenhas, MD, discussed the evolving role of JAK inhibitors for the treatment of patients with myelofibrosis, including new agents under evaluation in randomized studies and potential combination strategies that may also improve outcomes.

New Therapies in Development for Myelofibrosis

October 15, 2020

Building on the transformative impetus from the first FDA-approved JAK 1/2 inhibitor, ruxolitinib, in the clinical landscape of myeloproliferative neoplasms, we are entering a new era of multiple JAK inhibitors and other diverse classes of drugs in rapid clinical development.