Aditya Bardia, MBBS, MPH

Aditya Bardia, MBBS, MPH, a medical oncologist at Massachusetts General Hospital, discusses the value of liquid biopsies in the treatment landscape of breast cancer. The real value of liquid biopsy in this space lies in providing oncologists with insight on what&rsquo;s happening in tumor evolution, says Bardia.

The use of liquid biopsies will improve upon the oncologist&rsquo;s understanding of the disease and the patient at hand. With a better understanding of this, oncologists can give targeted therapies that target specific mutations, ultimately resulting in improved outcomes for these patients.

FDA approved alpelisib (Piqray), a PI3K inhibitor

, for the treatment of patients with HR-positive, HER2-negative,

-mutated, advanced or metastatic breast cancer, following progression on or after an endocrine-based therapy.

mutations are most common in patients with HR-positive breast cancer. Bardia says this agent is the beginning of the integration of precision medicine into breast cancer management.

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Aditya Bardia, MBBS, MPH, discusses the value of liquid biopsies in the treatment landscape of breast cancer. The real value of liquid biopsy in this space lies in providing oncologists with insight on what&rsquo;s happening in tumor evolution.

Evaluating the Role of Liquid Biopsy in Breast Cancer

Aditya Bardia, MBBS, MPH, a breast medical oncologist at Massachusetts General Hospital and Harvard Medical School, discusses the development of targeted therapies for patients with triple-negative breast cancer (TNBC). He says these approaches can be divided into 3 different categories.

The first category would be targeting oncogenes. An example of this would be the use of PARP inhibitors. Second, ongoing trials are also looking at intercellular signaling pathways, says Bardia.

Aditya Bardia, MBBS, MPH, discusses the development of targeted therapies for patients with triple-negative breast cancer. He says these approaches can be divided into 3 different categories.

Aditya Bardia, MBBS, MPH | Authors

Articles

Evaluating the Role of Liquid Biopsy in Breast Cancer

Evaluating 3 Types of Targeted Therapies for Triple-Negative Breast Cancer