2017 August | The Journal of Targeted Therapies in Cancer

Savolitinib, Small-Molecule MET Kinase Inhibitor, Demonstrates Safety and Efficacy in Phase II Study

September 22, 2017

Clinical Articles

Patients with metastatic papillary renal cell carcinoma have limited therapeutic options, but results of a phase II safety and efficacy study suggest that a small-molecule inhibitor, savolitinib, could help patients with MET-driven disease.

Engineering Chimeric Antigen Receptor T Cells to Treat Glioblastoma

August 18, 2017

Clinical Articles

The authors share their experience with EGFRvIII-specific chimeric antigen receptors, which they hope will contribute to the growing body of research committed to discovering a novel therapy for glioblastoma.