2017 October | The Journal of Targeted Therapies in Cancer

Overview of Merkel Cell Carcinoma

January 02, 2018

Clinical Articles

Merkel cell carcinoma (MCC) is a rare but potentially lethal skin cancer that has traditionally been treated with surgery, radiation, and in advanced cases, chemotherapy. Patients with even localized disease have a high risk of recurrence and those who develop metastatic disease have had a poor overall survival.

T Cell-Resistant Cancer Genes Identified by Genome-Scale CRISPR Screen

November 14, 2017

Clinical Articles

A new study published in the August 7 issue of Nature identified genes that are necessary in cancer cells for immunotherapy to work, addressing the problem of why some tumors do not respond to immunotherapy or respond initially but then stop as tumor cells develop resistance to immunotherapy.

Serum Tumor Markers Used to Monitor Therapeutic Outcomes in NSCLC

November 13, 2017

Clinical Articles

Four tumor serum markers commonly used in other solid tumors could be used in monitoring therapeutic outcomes in patients with stage IV lung adenocarcinoma, according to a single-center retrospective analysis.