Personalized Therapies in Advanced Breast Cancer

Debu Tripathy, MD, co-leader, Women's Cancer Program, University of Southern California Norris Comprehensive Cancer Center, discusses new personalized therapies on the horizon for advanced breast cancer.

Clinical Pearls:

• Physicians have known for some time that there are molecular targets that are amenable to therapy
• Now that the entire genome can be sequenced, physicians are understanding more about mutations in breast cancer
• Upon sequencing the tumors of many patients with breast cancer, physicians are finding that no two tumors are the same
• New mutations may be picked up after analyzing a patient’s tumor after treatment