Treatment Options for Multicentric Castleman's Disease

Siltuximab is now approved for multicentric Castleman’s disease > >

Clinical Pearls

Frits van Rhee, MD, PhD, MRCP, professor of medicine, Myeloma Institute for Research and Therapy, University of Arkansas for Medical Sciences, discusses treatment options for multicentric Castleman's disease.

• Multicentric Castleman's disease is a benign lymph node disorder in which patients get sick and notice lumps and bumps.
• There is currently no standard of care for this group of patients who are not infected with HIV.
• Being a rare disease, there have been no large studies conducted in this space.
• Steroids and rituximab are commonly used to treat this disease.