Metastatic Prostate Cancer with Charles Ryan, MD and William K. Oh, MD: Case 1 - Episode 10
Are there any side effects for prednisone in combination with abiraterone that are concerning for these patients?
Some people are concerned about whether prednisone might, in fact, increase the risks of abiraterone but in my practice I have not found that to be a significant concern. There are some patients who might develop some increased bruising, some patients might develop hyperglycemia, but for the most part because the dose is so low, only 10 mg a day, we have not had trouble administering abiraterone/prednisone to most of our patients, even if they’re prediabetic, for example, as long as they’re monitored closely.
CASE: Metastatic Prostate Cancer (Part 1)
Stanley S is an 83-year-old Caucasian male whose past medical history includes diagnosis of adenocarcinoma of the prostate in 2012 with no evidence of metastasis. At the time, he was started on bicalutamide and his serum PSA levels subsequently decreased to 1.2 ng/ml.
During his most recent follow-up exam, the patient complained of intermittent back pain and increasing fatigue.