Andrew D. Smith | Authors

Articles

Pushing Ahead With New Treatments for Nonmetastatic Castration-Resistant Prostate Cancer

September 22, 2018

Patients with the localized form of CRPC still have no options that are proven to extend overall survival, but preliminary results from the PROSPER trial of enzalutamide and the SPARTAN trial of apalutamide offer them unprecedented hope.

Trials Consider Role of Immunotherapy in Breast Cancer

March 28, 2018

Mixed results have occured in recent trials testing immuotherapy in patients with breast cancer. Checkpoint inhibitors have been used as monotherapy in a pair of trials, reporting lackluster overall response rates. When immunotherapy was paired with chemotherapy, on the other hand, it usually showed better results, and gave signals that immunotherapies combined with targeted agents could work better than immunotherapy alone.