Novel Approaches Tackle the JAK Pathway Beyond Ruxolitinib and Myelofibrosis
March 21, 2018
Since the identification of the role of the JAK kinase family in the late 1980s, awareness of this has grown significantly. These tyrosine
kinases have been proven to transmit a variety of signals into the cells with many biological consequences, adding to the interest in the targetability of the JAK pathway. However, better understanding of the complexities of JAK signaling are being evaluated in clinical trials.