Cirmtuzumab Blocks Ovarian Cancer Metastasis in Preclinical Study
The monoclonal antibody cirmtuzumab, currently in clinical trials to treat CLL, targets ROR1 on the surface of cancerous B cells, and the agent may have a wider reach in the treatment of ovarian and other cancers.
HIV Has Role in CAR-T Therapy
Recent news stories profiling a cancer patient whose last hope rests on treatment by injections of the virus that causes AIDS may have created some misconceptions regarding a new cancer immunotherapy.
Lesions Leading to Pancreatic Cancer Reduced With Anti-ICAM-1 Antibody
Researchers from the Mayo Clinic in Jacksonville, Florida, have uncovered the link between oncogenic pancreatic acinar cells and the inflammation that facilitates its cancerous progression.
Trials Show Efficacy of BRCA-Targeted Agent in Prostate Cancer
Drugs that inhibit the DNA repair enzyme poly(ADP-ribose) polymerase (PARP) have been shown to be effective in treating ovarian, breast, and prostate cancers in patients with inherited BRCA mutations.
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