June 2014 | The Journal of Targeted Therapies in Cancer

HPV Test With Genotyping Supplants Pap Test

August 08, 2014

Clinical Articles

Cervical cancer screening based on identification of human papillomavirus (HPV) outperformed primary liquid cytology for detection of high-grade cervical intraepithelial neoplasia (CIN).

Bromodomain Inhibitor Shows Activity in Hematologic Malignancies

August 05, 2014

Clinical Articles

The bromodomain inhibitor, OTX015, may have use in the treatment of hematologic malignancies, including acute leukemia and other hematologic malignancies that include lymphomas and multiple myeloma.

CD19-Targeted Agents Continue to Show Positive Outcomes

August 01, 2014

Clinical Articles

For nearly 2 decades, researchers have been exploring B-cell–specific antigens in hopes of developing a new anticancer target that could surpass the success of CD20-targeting agents.

A Long-Awaited Treatment Option for Radioiodine- Refractory DTC

June 30, 2014

Clinical Articles

The combination of surgery, radioactive iodine (RAI), and L-thyroxine therapy is effective treatment for patients with differentiated thyroid cancer (DTC), which accounts for some 95% of all thyroid cancers.

Targeting Radiotherapy in the Liver: SIR-Spheres®

June 23, 2014

Clinical Articles

The liver is a common site of metastatic recurrence for many tumors. For a minority of patients, surgical resection may be an option; however, most patients will not qualify for surgery due to insufficient liver functional reserve or other contraindications.