Dr. Abraham Chachoua on Anti-PD-1 and Anti-PD-L1 Treatments in Lung Cancer
Abraham Chachoua, MD, associate professor of Oncology, NYU Langone Medical Center, talks about the present use of anti-PD-1 and anti-PD-L1 becoming the standard second-line treatment in lung cancer.
Abraham Chachoua, MD, associate professor of Oncology, NYU Langone Medical Center, talks about the present use of anti-PD-1 and anti-PD-L1 treatments becoming the standard second-line treatment in lung cancer. He says that the treatments could become frontline treatments in the future, as single agents or in combination with other treatments, which is something researchers are currently working on.
Chachoua says one treatment in particular, nivolumab, was approved for squamous carcinoma and non-squamous carcinoma based on the CHECKMATE-057 trial. He adds that treatments like pembrolizumab were approved as well, though for patients that have PD-1 expression of greater than 50%. Chachoua said deciding who to test for PD-1 expression and who to give these treatments to is entirely up to the discretion of oncologists based on each individual patient.
Landgren on MRD as an End Point for Multiple Myeloma Trials
May 1st 2024C. Ola Landgren, MD, PhD, discussed the FDA’s unanimous ODAC vote supporting minimal residual disease as an accelerated approval end point in multiple myeloma and the implications of this vote in the myeloma research field.
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Nogapendekin Alfa Plus Checkpoint Inhibition Improves Survival in NSCLC
April 25th 2024Following its recent FDA approval in non-muscle-invasive bladder cancer, nogapendekin alfa has also shown overall survival benefits in addition to checkpoint inhibitor therapy in patients with non-small cell lung cancer.
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