HER2+ Early-Stage Breast Cancer with Ruth O'Regan, MD Case 2

Video

HER2+ Early-Stage Breast Cancer with Ruth O'Regan, MD

Case Scenario 2:

  • This is a 33-year old pre-menopausal woman who, after palpating a mass in her left breast, was referred for a mammogram by her primary care physician. Family history includes a sister who died of breast cancer at age 43 years.

  • Her mammogram revealed a spiculated mass in the upper outer quadrant of the left breast. Targeted ultrasound showed a 2.6 x 3.4 x 2.1 cm irregular mass with an indistinct margin. Prominent appearing right axillary lymph nodes.
  • Pathology: core biopsy revealed an invasive ductal carcinoma, poorly differentiated, lymphovascular invasion present. The tumor sample was mammaglobin-positive, ER/PR-negative, and HER2 3+ by IHC. Axillary ultrasound with fine-needle aspiration which was also positive for nodal involvement.
  • The case was presented at the breast cancer multidisciplinary tumor board. The team recommended neoadjuvant therapy before surgery.
Related Videos
Erika P. Hamilton, MD, and the Oncology Brothers presenting slides
Erika P. Hamilton, MD, and the Oncology Brothers presenting slides
Erika P. Hamilton, MD, and the Oncology Brothers presenting slides
Erika P. Hamilton, MD, and the Oncology Brothers presenting slides
Erika P. Hamilton, MD, and the Oncology Brothers presenting slides
Related Content