Evolving Paradigms in Pancreatic Cancer: References

Evolving ParadigmsPancreatic Cancer

Evolving Paradigms in Pancreatic Cancer: References

Evolving Paradigms in Pancreatic Cancer: Frontline Treatment Regimens

Reference 7:Minimizing Adverse Events With Dose Modification in Pancreatic Cancer

References 8-10:Factors Determining Frontline Therapy Selection for Pancreatic Cancer

References 11-13:Second-Line Options Allow for Treatment Sequencing in Pancreatic Cancer

Reference 14:Earlier Use on Horizon for Novel Agents in Pancreatic Cancer

References 15-20:New Agents Under Exploration in Pancreatic Cancer


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  12. Chen L-T, Von Hoff DD, Li C-P, et al. Expanded analyses of NAPOLI-1: Phase 3 study of MM-398 (nal-IRI), with or without 5-fluorouracil and leucovorin, versus 5-fluorouracil and leucovorin, in metastatic pancreatic cancer (mPAC) previously treated with gemcitabine-based therapy.J Clin Oncol. 2015;33 (suppl 3; abstr 234).
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  14. Peterson S, Loaiza-Bonilla A, Ben-Josef E, et al. Neoadjuvant nab-paclitaxel and gemcitabine (AG) in borderline resectable (BR) or unresectable (UR) locally advanced pancreatic adenocarcinoma (LAPC) in patients ineligible for FOLFIRINOX.J Clin Oncol. 2016;34 (suppl 4S; abstr 328).
  15. Hingorani SR, Harris WP, Hendifar AE, et al. High response rate and PFS with PEGPH20 added to nab-paclitaxel/gemcitabine in stage IV previously untreated pancreatic cancer patients with high-HA tumors: Interim results of a randomized phase II study.J Clin Oncol. 2015;33 (suppl; abstr 4006).
  16. Hidalgo M, Cooray P, Carrato A, et al. A phase 1b study of the anti-cancer stem cell agent demcizumab (DEM) and gemcitabine (GEM) +/- nab-paclitaxel in patients with pancreatic cancer.J Clin Oncol. 2016;34 (suppl 4S; abstr 341).
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  20. Le DT, Wang-Gillam A, Picozzi V Jr, et al. A phase 2, randomized trial of GVAX Pancreas and CRS-207 immunotherapy versus GVAX alone in patients with metastatic pancreatic adenocarcinoma: Updated results. Presented at: the ASCO Gastrointestinal Cancers Symposium; January 16-18, 2014; San Francisco, California. Abstract 177.
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