Updated phase 2 data showed a 60% ORR and 86% CNS ORR with frontline silevertinib in non-classical EGFR-mutant NSCLC; FDA discussion supported a phase 3 trial in 2027.
|Videos|November 4, 2013
The Utility of Afatinib in Lung Cancer
Author(s)Tony S.K. Mok, BMSc, MD, FRCPC
Tony S.K. Mok, BMSc, MD, FRCPC, professor, Department of Clinical Oncology, Chinese University of Hong Kong, Prince of Wales Hospital Hong Kong, China, discusses the utility of afatinib in patients with lung cancer.
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Clinical Pearls
Tony S.K. Mok, BMSc, MD, FRCPC, professor, Department of Clinical Oncology, Chinese University of Hong Kong, Prince of Wales Hospital Hong Kong, China, discusses the utility of afatinib in patients with lung cancer.
- Results from the LUX-Lung 3 trial demonstrated benefit with afatinib compared with cisplatin/pemetrexed in patients with advanced lung adenocarcinoma withEGFRmutations
- Afatinib is now available in the U.S.
- How afatinib compares with other TKIs is still up for debate
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