Daniel S. Oh, MD, assistant professor of surgery, University of Southern California, Keck School of Medicine, discusses myPlan genetic testing in patients with lung cancer.
Daniel S. Oh, MD, assistant professor of surgery, University of Southern California, Keck School of Medicine, discusses myPlan genetic testing in patients with lung cancer.
MyPlan is a molecular diagnostics test that uses the paraffin embedded surgical resection specimen, as well as representative slides, says Dr. Oh. A real-time PCR-based platform is then conducted, and it is run on gene-expression of some cell cycle progression genes. The scoring system is combined with the clinical stage, which produces the prognostic score, which is stratified into high-risk and low-risk.
Typically, myPlan is used on stage I and stage II patients with lung cancer, adds Oh. It is particularly useful for stage Ib because there is a lot of controversy over who to treat with chemotherapy. Oh says it is also useful for stage II patients because they have a very wide distribution of risk; some with high-risk and some with low-risk.
Nogapendekin Alfa Plus Checkpoint Inhibition Improves Survival in NSCLC
April 25th 2024Following its recent FDA approval in non-muscle-invasive bladder cancer, nogapendekin alfa has also shown overall survival benefits in addition to checkpoint inhibitor therapy in patients with non-small cell lung cancer.
Read More