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Opinion|Videos|December 7, 2023

Overview of the Mechanism of Action of TAR-200 in Patients With BCG-Unresponsive High-Risk NMIBC

Author(s)Siamak Daneshmand, MD

The TAR-200 treatment for BCG-unresponsive NMIBC works through a catheter-placed intravesical device that elutes gemcitabine over 3 weeks, providing a high complete response rate of 77% in early testing, likely due to the sustained release mechanism.

Episodes in this series

EP. 1 An Overview of BCG-Unresponsive Non-Muscle-Invasive Bladder Cancer (NMIBC)

EP. 1 An Overview of BCG-Unresponsive Non-Muscle-Invasive Bladder Cancer (NMIBC)

EP. 2 Current Standard-of-Care Treatment for Patients With BCG-Unresponsive High-Risk NMIBC

EP. 2 Current Standard-of-Care Treatment for Patients With BCG-Unresponsive High-Risk NMIBC

EP. 3 Overview of the Mechanism of Action of TAR-200 in Patients With BCG-Unresponsive High-Risk NMIBC

EP. 3 Overview of the Mechanism of Action of TAR-200 in Patients With BCG-Unresponsive High-Risk NMIBC

EP. 4 Safety Data From the Phase 2B SunRISe-2 Study of TAR-200 in BCG-Unresponsive High-Risk NMIBC

EP. 4 Safety Data From the Phase 2B SunRISe-2 Study of TAR-200 in BCG-Unresponsive High-Risk NMIBC

EP. 5 Identifying Patients With BCG-Unresponsive High-Risk NMIBC Suitable for Treatment With TAR-200

EP. 5 Identifying Patients With BCG-Unresponsive High-Risk NMIBC Suitable for Treatment With TAR-200

EP. 6 Other Key Trials in the Treatment of BCG-Unresponsive High-Risk NMIBC

EP. 6 Other Key Trials in the Treatment of BCG-Unresponsive High-Risk NMIBC

EP. 7 Clinical Pearls for Oncologists Treating Patients With BCG-Unresponsive NMIBC

EP. 7 Clinical Pearls for Oncologists Treating Patients With BCG-Unresponsive NMIBC

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