Opinion|Videos|July 24, 2024

Updates from the CAPTIVATE Study Evaluating Ibrutinib + Venetoclax in TN CLL/SLL

Author(s)Mazyar Shadman, MD, MPH

An expert on hematologic malignancies discusses the ongoing CAPTIVATE trial evaluating ibrutinib plus venetoclax in patients with treatment-naïve CLL/SLL.

Episodes in this series

Mazyar Shadman, MD, MPH, an expert on CLL

EP. 1 Clinical Approaches in High-Risk Patients with CLL/SLL

Mazyar Shadman, MD, MPH, an expert on CLL

EP. 2 SEQUOIA Arm D Study: Zanubrutinib plus Venetoclax in Treatment-Naive CLL/SLL with del(17p) and/or TP53 Mutations

Mazyar Shadman, MD, MPH, an expert on CLL

EP. 3 Updates from the CAPTIVATE Study Evaluating Ibrutinib + Venetoclax in TN CLL/SLL

Mazyar Shadman, MD, MPH, an expert on CLL

EP. 4 Future Implications of Combination Regimens and Treatment Duration in CLL/SLL

Mazyar Shadman, MD, MPH, an expert on CLL

EP. 5 Examining Toxicity Management of BTK Inhibitors for CLL/SLL

Mazyar Shadman, MD, MPH, an expert on CLL

EP. 6 Treatment Paradigms for Clinical Progression of CLL/SLL Beyond Initial Therapies

Mazyar Shadman, MD, MPH, an expert on CLL

EP. 7 Perspectives on Indirect Comparisons of BTK Inhibitors for R/R CLL/SLL

Mazyar Shadman, MD, MPH, an expert on CLL

EP. 8 Additional Data and Key Takeaways in CLL/SLL from EHA 2024

Mazyar Shadman, MD, MPH, an expert on CLL

EP. 9 Future Outlooks in the Treatment of CLL/SLL

Video content above is prompted by the following questions:

Please briefly discuss the ongoing CAPITIVATE trial, evaluating ibrutinib plus venetoclax for the treatment of treatment naïve CLL/SLL.
- Please discuss the latest data from the CAPTIVATE trial.
  - What are the key takeaways from the results of this study?
  - How do the outcomes impact patients with high-risk genomic features?

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