Roundtable Roundup: Polling Physicians on Timing of Durvalumab in NSCLC

Case-Based Roundtable Meetings Spotlight, Case-Based Roundtable Meetings Spotlight August 2021: Solid Tumors,
Pages: 74

During separate virtual live events, David R. Gandara, MD, and Alexander Spira, MD, PhD, discussed the timing of durvalumab in non–small cell lung cancer from the PACIFIC trial with participating physicians.

“In your practice, what is the typical time to initiation of durvalumab following completion of concurrent chemoradiotherapy for patients with unresectable stage III non–small cell lung cancer?”

"I think 21 to 40 days is right where I would think we should be. I’m a little skeptical of giving durvalumab right at the completion of chemoradiation for a variety of reasons.”

—DAVID R. GANDARA, MD

Most of us are trying to get into that 4- to 6-week period. A couple of us try a bit earlier. I’ll tell you my experience is that patients need a little bit of a break, but I think we’re all pretty reasonable. I always say what I like to do is 21 to 40 days, but we always have people who are just not feeling well or need to go on that vacation [from therapy].”

—ALEXANDER SPIRA, MD, PHD