This roundtable series examines systemic treatment in patients with desmoid tumors which have progressed, as discussed by key opinion leaders at virtual live events and interviews.

Treating Patients With Progressing Desmoid Tumors

Applying Desmoid Tumor Treatment Strategies and Data in Practice

September 22, 2025

During a live event, Steven I. Robinson, MBBS, discussed guideline-concordant active surveillance and systemic therapies for managing desmoid tumors.

Understanding Desmoid Tumor Rates, Diagnosis, and Concerns

August 21, 2025

During a live event, Steven I. Robinson, MBBS, discussed desmoid tumor statistics and management for symptomatic progression.

Monitoring Desmoid Tumor Progression with Strategic Imaging Intervals

August 07, 2025

During a live event, Tony Philip, MD, recommended tailored imaging intervals and avoiding surgery and radiation for desmoid tumors.

Managing Desmoid Tumors With Molecular Profiling and Recent Guidelines

July 17, 2025

During a live event, Tony Philip, MD, and participants discussed molecular profiling and active surveillance for desmoid tumor management.

DeFi Study Establishes Role of Nirogacestat in Desmoid Tumors

April 21, 2025

During a live event, Richard F. Riedel, MD, discussed key efficacy and safety outcomes from the phase 3 DeFi trial in patients with progressing desmoid tumors.

Active Surveillance Approach Can Avoid Treatment for Desmoid Tumors

April 17, 2025

During a live event, Richard F. Riedel, MD, discussed Desmoid Tumor Working Group and NCCN guidelines for treating patients with desmoid tumors.

Evaluating Survival, Long-Term Use of Nirogacestat in Desmoid Tumors

March 05, 2025

Nam Quoc Bui, MD, discusses survival, symptom control, and ovarian toxicity in the DeFi trial of nirogacestat in patients with desmoid tumors.

Balancing Symptoms and Current Therapies in Desmoid Tumor Management

February 12, 2025

During a live event, Nam Quoc Bui, MD discussed desmoid tumors, their presentation, and treatment.

Nirogacestat Shows Improved PFS and Quick Response in Desmoid Tumors

January 14, 2025

Mark Agulnik, MD, discusses the efficacy and adverse events in the DeFi trial for patients with desmoid tumors given nirogacestat.

Understanding When to Choose Systemic Treatment for Desmoid Tumors

December 23, 2024

Mark Agulnik, MD, discusses the intricacies of desmoid tumors that can be recognized before starting treatment for patients.