Dr. Kuykendall provides his perspective on the biggest unmet needs with current advanced PV therapies, emerging data he is following that may impact future management, and any other clinical pearls for optimal PV management.
Case: Management of Advanced Polycythemia Vera in a 67-Year-Old-Male
Clinical Presentation:
Initial Clinical Workup and Diagnosis:
Initial Treatments:
Disease Progression and Subsequent Treatments:
February 2019
FDA Enforces Partial Hold on Trial of Seclidemstat in MDS/CMML
July 16th 2024Following the report of a serious and unexpected grade 4 adverse effect, a partial clinical hold has been placed on the phase 1 trial evaluating seclidemstat with azacitidine in myelodysplastic syndrome and chronic myelomonocytic leukemia.
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